{"product_id":"alfa-1-antitrypsine-1","title":"Alpha-1 antitrypsin","description":"\u003cdiv class=\"content_text\"\u003e\n\u003cp\u003e\u003cstrong\u003eIndication\u003c\/strong\u003e: Detection of intestinal inflammations, Leaky Gut Syndrome, and food intolerances.\u003c\/p\u003e\n\u003cp\u003eAlpha-1-antitrypsin (α-1-antitrypsin) is an anti-inflammatory agent, produced in liver and intestinal cells. The liver produces 2 grams per day.\u003c\/p\u003e\n\u003cp\u003eIt is an acute-phase protein that, among other things, inhibits inflammatory enzymes and has anti-proteolytic effects. For example, α-1-antitrypsin inhibits the action of the enzyme elastase. Elastase breaks down elastin, an important component of connective tissue. Alpha-1-antitrypsin is measured in feces and is highly suitable for detecting inflammations at a very early stage.\u003c\/p\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/www.rpsh.nl\/data\/cms_uploads\/files\/source\/Onderzoeken%20SAP%20-%20informatieve%20afbeeldingen\/Alpha-1-antitrypsine.png?1584726719304\" alt=\"\" width=\"450\" height=\"285\" class=\"loaded\" data-was-processed=\"true\"\u003e\u003c\/p\u003e\n\u003cp\u003eNB: Alpha-1-antitrypsin increases over time as inflammation increases. However, α-1-antitrypsin will decrease if the inflammation increases beyond what α-1-antitrypsin can control. Therefore, the analytical value should always be assessed alongside inflammatory markers such as \u003ca href=\"https:\/\/www.rpsh.nl\/rpsh-analytic\/parameters\/ontsteking-darmontstekingen-en-darmpermeabiliteit\/calprotectine\/\" rel=\"noopener\"\u003ecalprotectin\u003c\/a\u003e, \u003ca href=\"https:\/\/www.rpsh.nl\/rpsh-analytic\/parameters\/ontsteking-darmontstekingen-en-darmpermeabiliteit\/pmn-elastase-polymorfonucleaire-elastase\/\" rel=\"noopener\"\u003ePMN Elastase\u003c\/a\u003e, \u003ca href=\"https:\/\/www.rpsh.nl\/rpsh-analytic\/parameters\/ontsteking-darmontsteking-en-darmpermeabiliteit\/lysozyme\/\" rel=\"noopener\"\u003elysozyme\u003c\/a\u003e, \u003ca href=\"https:\/\/www.rpsh.nl\/rpsh-analytic\/parameters\/ontsteking-darmontsteking-en-darmpermeabiliteit\/wrcrp\/\" rel=\"noopener\"\u003ewrCRP\u003c\/a\u003e and \u003ca href=\"https:\/\/www.rpsh.nl\/rpsh-analytic\/parameters\/ontsteking-darmontsteking-en-darmpermeabiliteit\/lactoferrine\/\" rel=\"noopener\"\u003elactoferrin\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"title\"\u003e\n\u003ch2\u003eReference Value\u003c\/h2\u003e\n\u003ctable style=\"height: 211px;\" width=\"498\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 168.45px;\"\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003eAlpha-1-antitrypsine\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 77.825px;\"\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003eMax.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 232.925px;\"\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003eUnit\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 168.45px;\"\u003e\n\u003cp\u003eReference value\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 77.825px;\"\u003e\n\u003cp\u003e\u0026lt; 27,5\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 232.925px;\"\u003e\n\u003cp\u003emg\/dL\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 168.45px;\"\u003e\n\u003cp\u003eTherapeutic value\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 77.825px;\"\u003e\n\u003cp\u003e\u0026lt; 24,8\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 232.925px;\"\u003e\n\u003cp\u003emg\/dL\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 168.45px;\"\u003e\n\u003cp\u003eEmpirical value\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 315.95px;\" colspan=\"2\"\u003e\n\u003cp\u003elow value may indicate an exhausted response\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"title\"\u003e\n\u003ch2\u003eInterpretation of test results\u003c\/h2\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"content_text\"\u003e\n\u003cp\u003e\u003cem\u003eElevated value\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eThere is anti-inflammatory activity. Therefore, inflammatory processes are ongoing against which alpha-1-antitrypsin is deployed as an anti-inflammatory agent. This may indicate the presence of intestinal inflammations (ulcerative colitis, Crohn's disease), food intolerances (celiac disease), or increased permeability of the intestinal epithelium (Leaky Gut Syndrome)\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eLow value\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eA low value of alpha-1-antitrypsin indicates that there is no anti-inflammatory activity. Therefore, no inflammatory reactions are ongoing, or the inflammatory reactions are greater than the anti-inflammatory capacity. Alpha-1-antitrypsin deficiency can lead to pulmonary emphysema and, to a lesser extent, liver cirrhosis.\u003c\/p\u003e\n\u003cdiv class=\"title\"\u003e\n\u003ch2\u003eUseful additional diagnostics\u003c\/h2\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"content_text\"\u003e\n\u003cp\u003e-\u003ca href=\"https:\/\/www.rpsh.nl\/rpsh-analytic\/onderzoeken\/ontstekingsscreening\/\" rel=\"noopener\"\u003eQualitative Inflammation package\u003c\/a\u003e (hemoglobin, transferrin, calprotectin, lactoferrin)\u003cbr\u003e-\u003ca href=\"https:\/\/www.rpsh.nl\/rpsh-analytic\/parameters\/ontsteking-darmontstekingen-en-darmpermeabiliteit\/calprotectine\/\" rel=\"noopener\"\u003eCalprotectin\u003c\/a\u003e (quantitative)\u003cbr\u003e-\u003ca href=\"https:\/\/www.rpsh.nl\/rpsh-analytic\/parameters\/ontsteking-darmontstekingen-en-darmpermeabiliteit\/pmn-elastase-polymorfonucleaire-elastase\/\" rel=\"noopener\"\u003ePMN Elastase\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"RPSH","offers":[{"title":"Default Title","offer_id":52693828239706,"sku":null,"price":45.0,"currency_code":"EUR","in_stock":true}],"url":"https:\/\/store.bloedcheckup.nl\/nl\/products\/alfa-1-antitrypsine-1","provider":"BloedCheckup","version":"1.0","type":"link"}