{"product_id":"creatinine","title":"Creatinine","description":"\u003ch2\u003eWhat is Creatinine?\u003c\/h2\u003e\n\u003cp\u003eCreatinine is a waste product that results from the normal breakdown of muscle tissue. It is transported through the bloodstream to the kidneys, where it is filtered and excreted through urine. Creatinine is an important biomarker for kidney function.\u003c\/p\u003e\n\n\u003ch2\u003eWhat is eGFR and CKD-EPI?\u003c\/h2\u003e\n\u003cp\u003eThe \u003cstrong\u003eeGFR (estimated Glomerular Filtration Rate)\u003c\/strong\u003e is a calculation that provides an estimate of how well your kidneys are functioning. It is calculated using the \u003cstrong\u003eCKD-EPI formula\u003c\/strong\u003e (Chronic Kidney Disease Epidemiology Collaboration), the most accurate and current formula for estimating kidney function.\u003c\/p\u003e\n\n\u003cp\u003eThe CKD-EPI formula uses:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eYour creatinine value\u003c\/li\u003e\n\u003cli\u003eAge\u003c\/li\u003e\n\u003cli\u003eGender\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eThe eGFR indicates how much blood (in milliliters) your kidneys can filter per minute per 1.73m² body surface area. This provides a much more accurate picture of kidney function than creatinine alone.\u003c\/p\u003e\n\n\u003ch2\u003eWhy would you test Creatinine and eGFR?\u003c\/h2\u003e\n\u003cp\u003eTesting creatinine and calculating eGFR is essential for assessing kidney function. This combination provides the most complete picture of how well your kidneys are working. The test is used for:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eRoutine check-ups and preventive screening\u003c\/li\u003e\n\u003cli\u003eSuspected kidney disease\u003c\/li\u003e\n\u003cli\u003eMonitoring known kidney diseases\u003c\/li\u003e\n\u003cli\u003eAssessment of medication dosing (many medications are excreted through the kidneys)\u003c\/li\u003e\n\u003cli\u003eEvaluation of risk factors such as diabetes and high blood pressure\u003c\/li\u003e\n\u003cli\u003eScreening for family history of kidney disease\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eWhat does it indicate?\u003c\/h2\u003e\n\u003cp\u003eThe eGFR is the primary indicator of kidney function and is classified into different stages:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003e≥90 mL\/min\/1.73m²:\u003c\/strong\u003e Normal to excellent kidney function (stage 1)\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003e60-89 mL\/min\/1.73m²:\u003c\/strong\u003e Mildly decreased kidney function (stage 2)\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003e45-59 mL\/min\/1.73m²:\u003c\/strong\u003e Moderately decreased kidney function (stage 3a)\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003e30-44 mL\/min\/1.73m²:\u003c\/strong\u003e Moderately to severely decreased kidney function (stage 3b)\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003e15-29 mL\/min\/1.73m²:\u003c\/strong\u003e Severely decreased kidney function (stage 4)\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003e\u0026lt;15 mL\/min\/1.73m²:\u003c\/strong\u003e Kidney failure, dialysis may be needed (stage 5)\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eWhat does elevated Creatinine \/ low eGFR mean?\u003c\/h2\u003e\n\u003cp\u003eElevated creatinine and low eGFR indicate decreased kidney function. The kidneys are less able to effectively filter waste products from the blood. Possible causes include:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eChronic kidney disease (most common)\u003c\/li\u003e\n\u003cli\u003eAcute kidney injury\u003c\/li\u003e\n\u003cli\u003eDehydration (temporary)\u003c\/li\u003e\n\u003cli\u003eDiabetes or high blood pressure (damage kidneys over time)\u003c\/li\u003e\n\u003cli\u003eNephrotoxic medications (NSAIDs, certain antibiotics)\u003c\/li\u003e\n\u003cli\u003eKidney stones or urinary tract obstruction\u003c\/li\u003e\n\u003cli\u003eVery high muscle mass or intense training (can temporarily raise creatinine)\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eWhat does low Creatinine \/ high eGFR mean?\u003c\/h2\u003e\n\u003cp\u003eLow creatinine is less common and may indicate:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eDecreased muscle mass due to age, illness, or malnutrition\u003c\/li\u003e\n\u003cli\u003eSevere liver disease (reduced creatine production)\u003c\/li\u003e\n\u003cli\u003ePregnancy (physiologically decreased)\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eA very high eGFR (\u003e120 mL\/min\/1.73m²) is often normal in young, healthy people. It can also occur with hyperfiltration in early-stage diabetes, where the kidneys temporarily work harder.\u003c\/p\u003e\n\n\u003ch2\u003ePreparation\u003c\/h2\u003e\n\u003cp\u003eFor the most reliable results, it is recommended to:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eFast for 8-12 hours before the test\u003c\/li\u003e\n\u003cli\u003eAvoid heavy physical exercise 24 hours before the test\u003c\/li\u003e\n\u003cli\u003eBe well hydrated\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"BloedCheckup","offers":[{"title":"Default Title","offer_id":51995888615770,"sku":null,"price":17.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0814\/6816\/2394\/files\/CreatinekinaseCK_8ddd4beb-92b0-4433-85ae-180d33a36a0c.webp?v=1755941667","url":"https:\/\/store.bloedcheckup.nl\/nl\/products\/creatinine","provider":"BloedCheckup","version":"1.0","type":"link"}