{"product_id":"zonuline-feces","title":"Zonulin","description":"\u003cdiv class=\"content_text\"\u003e\n\u003cdiv class=\"content_text\"\u003e\n\u003cdiv class=\"content_text\"\u003e\n\u003cdiv class=\"content_text\"\u003e\n\u003cdiv class=\"content_text\"\u003e\n\u003cp\u003eZonulin is a protein that is active in the intestinal epithelium. Zonulin reacts to exposure to gliadin and pathogenic bacteria. Gliadin, together with glutenin, forms the protein gluten.\u003c\/p\u003e\n\u003cp\u003eAs soon as zonulin is released by the epithelial cells, it is signaled by Immunoglobulin A, after which a reaction of the intestinal wall follows. The tight junction proteins between the cells of the intestinal wall loosen or break. The gliadins or pathogenic bacteria can now pass through the intestinal wall, after which dendritic cells, via the antigen-presenting cells, trigger T-cell activation.\u003cbr\u003eThis immune response causes inflammation of the cells of the intestinal wall, after which zonulin, tight junction proteins, pathogens, bacterial lipopolysaccharides, and inflammatory mediating cytokines can enter the lamina propria from the intestines. Subsequently, these substances enter the bloodstream, where they can induce neuroinflammation.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"RPSH","offers":[{"title":"Default Title","offer_id":52772983013722,"sku":null,"price":140.0,"currency_code":"EUR","in_stock":true}],"url":"https:\/\/store.bloedcheckup.nl\/nl\/products\/zonuline-feces","provider":"BloedCheckup","version":"1.0","type":"link"}